Breakthrough Proves Natural Anti-aging Compound
It’s the old lottery winner story… Someone wins a big jackpot. Suddenly, everyone they ever knew declares himself a long-lost friend. But they just use the winner as a stepping-stone to the money.
I’ve just seen something like that happen with a nutritional supplement I’ve been recommending to you for years.
Two breakthroughs now prove that resveratrol – a plant compound found in grape skins, red wine, peanuts and berries – is an anti-aging powerhouse. In fact, these studies are so convincing that the race is now on to develop artificial compounds that act just like resveratrol.
Wait. Let’s back up for a second. We’re so sure we’ve confirmed the Holy Grail of anti-aging… we’re dumping it by the side of the road?
That’s right. The cash is in marketing drugs, not a natural compound. So the drug companies are now in an “arms race” to develop things that aren’t resveratrol, but act just like it.
You probably won’t hear the good news from them. So here’s what these breakthroughs mean to health-conscious folks like you.
It hasn’t been tested extensively in humans, but resveratrol has had remarkable results in animal studies. It’s a potent antioxidant. But it also powers up cells’ ability to generate energy. This – in turn – seems to lead to significant health gains:
- Give it to bees, mice and flies, and they all live longer.
- Mice taking resveratrol double their physical stamina.
- On resveratrol, mice seem almost immune to the effects of age and obesity.
But there have been problems. Scientists haven’t been sure exactly how resveratrol worked. So they couldn’t be 100% confident it responsible for these effects. The bets have been that it interacts with a protein called SIRT1 – an enzyme that’s known to affect longevity. But there hasn’t been absolute proof.
Until May of last year, that is. That’s when Harvard researchers announced they’d bred a mouse with an engineered “off switch” for SIRT1.
In ordinary mice – and engineered mice with the switch on – resveratrol switches on their cellular “generators.” But flip the switch off, and mice get no benefits from taking resveratrol.1
Now, a second Harvard-led study has filled in the one remaining puzzle piece. We now know how resveratrol interacts with SIRT1.2
The study is so convincing, it’s being reported as “conclusive evidence.” All that’s missing now are the human trials.
And there’s the problem. Drug companies won’t run these trials. Because resveratrol is natural, they can’t patent it. If they can’t patent it, they can’t make much money from it. So the race is on to create artificial compounds that work like resveratrol… which they can patent.
And we’re left with another orphan. But that doesn’t mean you can’t take advantage of resveratrol’s potential.
The few human trials to date are promising. For example, a team in Hungary discovered in 2011 that resveratrol promotes healthy insulin sensitivity.3 This shows it may support healthy blood sugar levels – a major health issue for millions.
And it’s already a proven antioxidant. Plus, we know it’s safe, and free of side effects. And it may also be behind “the French Paradox.”
The French eat a diet high in saturated fats. They also regularly drink red wine – a rich natural source of resveratrol – in moderate amounts. The French also have a remarkably low rate of serious health problems.
This is the French Paradox, and it appears to be something in the wine – resveratrol – that may be responsible.
So there are already plenty of good reasons to include resveratrol in your diet. There’s just one small problem.
A glass of red wine only contains about a half-milligram of resveratrol. It would take a lot of wine to get even close to the amounts used in studies. About 40 – 400 glasses a day… or more.
Fortunately, resveratrol is also available as a nutritional supplement. And considering its proven benefits, there’s really no reason to wait for more anti-aging studies to come in.
Yours in continued good health,
Best Life Herbals Wellness Team
1 Price, N.L., “SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function,” Cell Metab. May 2, 2012; 15(5): 675-690.
2 Hubbard, B.P., et al, “Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators,” Science. Mar 8, 2013; 339(6124): 1216-1219.
3 Brasnyó, P., et al, “Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients,” Br J Nutr. Aug 2011; 106(3): 383-389.