Potent Anti-Adhesion Action Helps Block Bladder Issues

Bladder problems. For most women, the question isn’t if you’ll have them, but when. Even worse, once you have a bladder or urinary tract (UT) issue, chances are good you’ll have another. And another. And another…

Bladder and UT issues cause almost 10 million doctor visits every year. Bacteria are behind most of these problems. And just one type of bacteria – E. coli – accounts for about 90% of bacterial issues.

I don’t have to tell you about the frustration and embarrassment of bladder/UT problems. Painful urination… sudden urges… those mortifying leaks… and more. The telltale stains. The odor. The humiliation.

No wonder so many women withdraw from their social lives when bladder/UT problems arise. Better to be absent than humiliated.

But wouldn’t it be better to stay connected? To shut down bladder problems? To discover lasting relief that holds E. coli at bay… for the long term?

Thanks to recent breakthroughs, we now understand how bacteria attack. And how to shut them down naturally. In a matter of just weeks, you could end your bladder/UT woes once and for all.

The secret is a principle we’ve put to work for you in Women’s Formula Ultimate Bladder Support.

Give Bladder Trouble the Bum’s Rush

You can argue with an unruly bum. But you’ll just be wasting your time. No level of argument will change a drunken bum’s opinion.

Your other option is to give him the “bums rush.” Just eject him from the scene before he can do any real damage.

That’s a key behind Women’s Formula Ultimate Bladder Support. Arguing with E. coli gets you nowhere. You have to give it the bum’s rush.

And we’ve uncovered Nature’s ideal “bouncers.” Compounds that give E. coli the bums rush… but don’t cause you any problems.

Both come from a familiar source. But they’re far more potent than that source. Which helps explain why some studies say the source isn’t very effective.

Proanthocyanidins Deliver Major Bladder Relief

It even takes experts a few tries to get “proanthocyanidins” right. It’s a fancy word for a very basic group of plant compounds.

PACs, as they’re sometimes called, have health-promoting effects. But PACs from cranberries appear to be unique. They interact with E. coli in ways that no other PACs do. They block E. coli’s ability to colonize your bladder and urinary tract.

  1. coli features connections with “adhesins.” These adhesins help bacteria grab hold of the lining of your bladder and urinary tract. And once a few E. coli have a good foothold, they start to spread.

The nasty bacteria colonize the area where they’ve gotten a foothold, and create a “biofilm” – and active bacterial colony.

A colony that damages its host is called an infection. And – believe me – E. coli can do a lot of damage. But here’s where the bum’s rush comes in.

Cranberry PACs react with E. coli in a way that makes it hard for the attacking bacteria to get a foothold. It’s what doctors call “anti-adhesion.” E. coli may try to grab onto the lining of your bladder/UT… but Cranberry PACs  prevent this.

So the bacteria get the bum’s rush. Most of them simply flush through your UT… and wind up flushed away, where they can’t hurt you.

Cranberry Extracts Are Better Than Juice

You may have read that cranberry juice is good for bladder problems. And then heard that it’s not all it’s cracked up to be. There’s a simple explanation:

There aren’t a lot of PACs in commercial cranberry juice.

In fact, most cranberry juice “cocktails” on the market today aren’t even close to real cranberry juice. They’ve been formulated to meet popular tastes. Which means less cranberry and more added sugars.

Sugars your body doesn’t need. But most people prefer sweetened cranberry juice because the fruit is so naturally tart. So commercial producers load lots of unhealthy sugars into their “ juice cocktails” to make them palatable.

Unfortunately, they also add to weight gain and blood sugar problems. Not exactly what you need on top of a bladder issue.

What you need is the active component found in cranberries. And you can get it.

From a Spotty Record to a Potent Ally

Decades of testing have led to no clear conclusions about cranberry juice and bladder/UT issues. Some studies have found a benefit… others no benefit at all. What’s going on?

The simplest explanation seems to be that many – if not most – cranberry juice products simply don’t have the levels of PACs they need to make a real difference.

But enough studies have shown a big enough benefit to make cranberry an intriguing potential remedy.

For example, a small 2006 study pointed to how effective cranberry can be…

In this study 10 healthy men and 10 healthy women drank one of four formulas in each of four sessions. The drinks included an inactive placebo, placebo plus mineral water, cranberry juice plus mineral water, or pure cranberry juice.

The groups took each of the formulas at random. But everyone eventually tried all four preparations. Because the study was double blind, neither the volunteers nor the doctors observing the study knew who got which drink when until after the study ended.

But the results were pretty clear. The more cranberry juice in the formula, the fewer bacteria were able to gain a foothold in the volunteers’ bladders and urinary tracts.1

Something in the cranberry juice was causing bacteria to flush through the volunteers’ systems. And blocking bladder problems.

Studies like these suggest cranberry can be effective. But studies of cranberry extracts have more even more consistent success.

More PACs = More Effective Defenses

In a 2009 study, scientists gave healthy volunteers 500 ml of unsweetened cranberry drink twice a day for a week. The doctors then compared the levels of dangerous bacteria in their subjects’ urine at the start and the end of the short study.

42% of their subjects saw a significant drop after just a week on the cranberry drink.2 That’s not bad… but it may help explain why some cranberry juice studies don’t show much benefit.

Then consider a study that compared the effect of PACs from cranberries to PACs from other fruits. The cranberry PACs showed anti-adhesion activity at levels of just 10 micrograms.

To get an idea of how small that amount is, there are just over 28 grams in an ounce. And there are one million micrograms in a gram!

The scientists used PACs from other fruits at levels up to 1200 micrograms… but none had a significant effect.3

It’s not cranberry juice that helps ease bladder problems. It’s the PACs unique to cranberries that do the heavy lifting. And you may not be able to get enough PACs to make a difference – even if you drink a liter of unsweetened juice per day.

A U.S. study tested PACs on women who’d had at least 6 bladder/UT problems in the prior year. For 12 weeks, the women took a cranberry concentrate high in PACs. None of them had bladder/UT issues during the 12 weeks.

Some women decided to continue taking the high-PAC concentrate after the study ended. Among those who did, none had a single bladder/UT issue in the following two years!4

Proof Upon Proof PACs Deliver Real Results

An international team of scientists published a study in BMC Infectious Diseases. They gave high-PAC cranberry extract or a placebo to women in 4 different countries.

Urine tests showed significant anti-adhesion activity in the women taking the cranberry extract. But not in the placebo group.5

In 2012, doctors in India tested cranberry PACs on drug-resistant bacteria. They exposed cell samples from human bladder/UT linings to these bacteria. In the presence of PACs, the bacteria weren’t able to get as firm a foothold as without the PACs.

In fact, the PACs blocked 70% of the bacteria from attaching to the cells.6

In a 2010 study, doctors tested PACs on women aged 18 to 65. Half of the volunteers had recurring bladder/UT issues. The other half didn’t.

Volunteers from each group were randomly assigned to receive either a cranberry extract or an inactive placebo for one week. Then, after a “washout” period, the two groups switched.

Neither the volunteers nor the doctors knew who was taking the cranberry extract at which time. So there could be no bias towards one regimen or the other.

And the results spoke for themselves. Urine samples from women during the cranberry regimen showed significant jumps in anti-adhesion activity compared to the placebo period.7

In other words, even if cranberry juice hasn’t worked for you, there’s a good chance cranberry extract will.

Which is why we’ve included 168 mg of cranberry extract in Women’s Formula Ultimate Bladder Support.

And that’s just for starters.

The Simple Secret That Turns Bacteria Into Their Own Worst Enemy

When bacteria begin to get a foothold in your bladder or UT, they often produce a chemical called nitrite. It’s a natural byproduct of their metabolism.

Scientists have discovered how to turn this byproduct into a weapon. One that blasts the bacteria that make the nitrite in the first place. And the secret is so simple, it may just surprise you.

It’s vitamin C.

Vitamin C works against bacteria in your bladder in two ways. First, it makes your urine more acidic… which is an unfriendly environment for most unfriendly bacteria.

But it’s the second way that really takes the cake. In an acid environment, nitrites form into nitric oxide and other forms of nitrogen oxides. And these oxides are deadly to certain types of bacteria – including E. coli.

Studies show that human urine containing nitrites forms nitric oxide and similar compounds… vitamin C significantly boosts the levels of these oxides in the urine… and these compounds inhibit the growth of several forms of unhealthy bacteria.8

In 2011, doctors gave vitamin C a tough challenge. They tested it on pregnant women.

Bladder problems are bad enough. But, as you can imagine, they’re even worse when you’re pregnant. (Or maybe you don’t have to imagine.) So doctors added just q00 mg of extra vitamin C to a pregnancy supplement.

For 3 months, half the volunteers took the regular supplement. The other half took the C-boosted version. During that time, almost a third of the first group had a bladder/UT issue. But the vitamin C group had less than half as many problems – under 13%.

Imagine that: Simply adding a little extra vitamin C cut the risk of bladder problems by more than half!

So you probably won’t be surprised to know Women’s Formula Ultimate Bladder Support delivers the same 100 mg of extra vitamin C that was so effective in this study.

Plus, you get the soothing action of marshmallow root… the flushing action of parsley leaf… and the calming effects of ginger. Along with 1 more potent bladder-boosting herbs and nutrients.

Women’s Formula Ultimate Bladder Support delivers the support your body needs to end the nightmare of bladder/UT problems. It’s 100% gentle… 100% natural…

And we promise they’ll work or your money back.

Your Peace of Mind is Guaranteed

Most supplements come with a 30-day satisfaction guarantee. That’s hardly enough time to decide if you’re happy. But it pretty much guarantees the company will make at least one sale for every customer.Women's Ultimate Bladder Support

Here at Best Life Herbals, we take a different approach. We want you to be happy – genuinely happy – with your supplements. So we offer a no-hassles full-year satisfaction guarantee. Even if you only order a 30-day supply.

With our formulas, you don’t have to rush to make up your mind. There’s no pressure. And no hassles. You’ll love our formulas, or we’ll buy them back. It’s that simple.

So you can try Women’s Formula Ultimate Bladder Support with no worries… and no risk. Plus, we offer another benefit many other supplement makers don’t:

Real savings opportunities.

Would you like to save up to 22% on every order? We’ll show you how. Does FREE shipping sound good? We can do it. Or would you like to save up to 35%… get FREE shipping… and never run out of Women’s Formula Ultimate Bladder Support?

We can do that, too.

If you’re ready for maximum relief… maxim savings… and maximum peace of mind, check out Women’s Formula Ultimate Bladder Support today.

Yours in continued good health,
The Best Life Herbals Wellness Team


The statements contained herein have not been evaluated by the US Food and Drug Administration. They are not intended to diagnose, prevent, treat or cure any disease.

1 Di Martino, P., et al, “Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial,” World Journal of Urology. Feb 2006; 24(1): 21-27.

2 Jass, J. and Reid, G., “Effect of cranberry drink on bacterial adhesion in vitro and vaginal microbiota in healthy females,” The Canadian Journal of Urology Dec 01, 2009; 16(6): 4901-4907.

3 “A-type cranberry proanthocyanidins and uropathogenic bacterial anti-adhesion activity,” Phytochemistry. Sep 2005; 66(18): 2281-2291.

4 Bailey, D.T., et al, “Can a concentrated cranberry extract prevent recurrent urinary tract infections in women? A pilot study,” Phytomedicine. Apr 10, 2007; 14(4): 237-241.

5 Howell, A.B., et al., “Dosage effect on uropathogenic Escherichia coli anti- adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study,” BMC Infectious Diseases. 2010; 10: 94.

6 Gupta, A., et al, “Inhibition of adherence of multi-drug resistant E. coli by proanthocyanidin,’ Urological Research. Apr 2012; 40(2): 143–150.

7 G. Tempera, et al, “Inhibitory Activity of Cranberry Extract on the Bacterial Adhesiveness in the Urine of Women: An Ex-vivo Study,” Intrntl Jrnl Immunopath and Pharma. Apr 2010; 23(2): 611-618.

8 Carlsson, S., et al, “Effects of pH, Nitrite, and Ascorbic Acid on Nonenzymatic Nitric Oxide Generation and Bacterial Growth in Urine,” Nitric Oxide. Dec 2001; 5(6): 580-586.

9 Ochoa, G.J., et al, “Daily intake of 100 mg ascorbic acid as urinary tract infection prophylactic agent during pregnancy,” AOGS. Jul 2007; 86(7): 783-787.

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